Achievement
Protecting therapeutic biomolecules
Project
NanoPharmaceutical Engineering and Science
University
Rutgers University New Brunswick
(New Brunswick, NJ)
PI
Research Achievements
Protecting therapeutic biomolecules
Trainee Kristin Gilida is working with Dr. Nina Shapley, Chem. & Biochem. Engineering to develop methods for protecting therapeutic biomolecules from photo-oxidation by encapsulation in polymeric particles. Using model therapeutic molecule beta carotene, Kristin found that significantly enhanced protection from photobleaching in a uniform polymer microparticle is provided by co-encapsulation with a combination of protective molecules consisting of an ultraviolet radiation absorber (oxybenzone) and an antioxidant (alpha-tocopherol). Kristin summarized her results in a talk at the AIChE 2010 annual meeting. In collaboration with two other laboratories at Brown University and the University of Massachusetts-Dartmouth, she is a co-author on a review article in press in the International Journal of Cosmetic Science and a research article submitted to Dyes and Pigments. In addition, Kristin has a first-author journal article in preparation, to be submitted in Spring 2011.
- “Research Achievements”
- Achievements for this Project